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pISSN 2005-9159
eISSN 2093-0569

Clinical Research Article

Korean J Pain 2023; 36(3): 382-391

Published online July 1, 2023 https://doi.org/10.3344/kjp.23114

Copyright © The Korean Pain Society.

Comparison of modified thoracoabdominal nerve block through perichondral approach and subcostal transversus abdominis plane block for pain management in laparoscopic cholecystectomy: a randomized-controlled trial

Hye-Yeon Cho1 , In Eob Hwang2 , Mirang Lee3 , Wooil Kwon3,4 , Won Ho Kim1,2 , Ho-Jin Lee1,2

1Department of Anesthesiology and Pain Medicine, Seoul National University College of Medicine, Seoul, Korea
2Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Korea
3Department of Surgery, Seoul National University Hospital, Seoul, Korea
4Department of Surgery, Seoul National University College of Medicine, Seoul, Korea

Correspondence to:Ho-Jin Lee
Department of Anesthesiology and Pain Medicine, Seoul National University College of Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul 03080, Korea
Tel: +82-2-2072-2467, Fax: +82-2-747-8363, E-mail: zenerdiode03@gmail.com

Handling Editor: Sang Hun Kim

Received: April 5, 2023; Revised: May 14, 2023; Accepted: June 3, 2023

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background: The modified thoracoabdominal nerve block through the perichondral approach (M-TAPA) is a novel regional analgesic technique that can provide analgesia for both the lateral and anterior abdominal walls. This study aimed to compare the analgesic effect of M-TAPA with that of the subcostal transversus abdominis plane block (TAPB) in patients undergoing laparoscopic cholecystectomy (LC).
Methods: Sixty patients scheduled to undergo elective LC were randomly assigned to receive either M-TAPA or subcostal TAPB during anesthesia induction. The primary outcome was the maximum pain intensity during movement within the first 12 hours postoperatively, measured using an 11-point numeric rating scale (NRS). Secondary outcomes included changes in NRS scores during rest, coughing, and movement, which were assessed at 1, 2, 4, 6, and 12 hours postoperatively and immediately before discharge. Additionally, postoperative nausea and vomiting, and patient satisfaction were recorded as secondary outcomes.
Results: Data from 56 patients were analyzed, and no significant difference was observed in the primary outcome between the two groups (M-TAPA: 5.5 [interquartile range (IQR): 5–7] vs . subcostal TAPB: 5 [IQR: 4–7], median difference: 0, 95% confidence interval: –1 to 1, P = 0.580). Furthermore, no significant differences in secondary outcomes were observed between the two groups.
Conclusions: No significant difference was observed in the analgesic effect between the two techniques. Consequently, further research is necessary to compare the efficacy of M-TAPA with other well-established regional analgesic techniques.

Keywords: Acute Pain, Cholecystectomy, Laparoscopic, Laparoscopy, Nerve Block, Pain, Postoperative, Patient Satisfaction, Postoperative Complications, Ultrasonography.