Results of the univariable and multivariable logistic regression analysis for chronic postsurgical pain

Variable name Univariable Multivariable
OR (95% CI) P value OR (95% CI) P value
Propofol-based total intravenous anesthesia 0.73 (0.56–0.96) 0.027 0.67 (0.50–0.89) 0.006
Female (vs. male) 1.48 (1.12–1.95) 0.006 1.62 (1.22–2.17) 0.001
Age 0.99 (0.98–1.01) 0.416
Body mass index (kg/m2) 0.96 (0.91–0.99) 0.046 0.96 (0.91–1.00) 0.051
ASA physical status (vs. I)
II 1.21 (0.75–1.97) 0.430
III 1.27 (0.68–2.37) 0.460
Smoking history 0.76 (0.52–1.11) 0.158
Extent of surgery (vs. wedge resection or metastatectomy)
Segmentectomy 1.51 (0.87–2.62) 0.142
Lobectomy 1.22 (0.76–1.96) 0.420
Others 0.81 (0.25–2.58) 0.717
History of taking analgesics 1.30 (0.81–2.11) 0.282
History of taking neuropsychiatric drugs 1.08 (0.63–1.82) 0.787
History of thoracic operation (ipsilateral) 1.76 (0.61–5.12) 0.299
Anesthesia duration (hr) 1.29 (1.06–1.58) 0.012 1.43 (1.16–1.77) < 0.001
Intraoperative remifentanil equivalent dose ≥ 0.2 µg /kg/min 1.57 (0.69–3.54) 0.281
Intraoperative regional analgesia 1.32 (0.89–1.96) 0.161
POD of chest tube removal ≥ 4 0.97 (0.73–1.28) 0.809
Maximum pain score at the discharge day 1.15 (1.01–1.31) 0.029 1.17 (1.02–1.33) 0.020

OR: odds ratio, CI: confidence interval, ASA: American Society of Anesthesiologists, POD: postoperative day.

Korean J Pain 2024;37:354~366 https://doi.org/10.3344/kjp.24173
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