Fig. 4. Intrathecal injection of lentiviral interference vector targeting miR-382-5p (LV-anti-miR-382-5p) inhibited the over-activation of proinflammatory factors in DRGs of CCI rats. (A–C) On day 21 of CCI surgery, the levels of proinflammatory factors (IL-6, IL-1β, TNF-α) in DRGs were measured by ELISA assay. Values are presented as mean ± standard deviation. DRGs: dorsal root ganglions, CCI: chronic constriction injury, IL-6: interleukin-6, IL-1β: interleukin-1β, TNF-α: tumor necrosis factor-α, ELISA: enzyme-linked immunosorbent assay. ***P < 0.001 vs. Sham. ###P < 0.001 vs. CCI + LV-anti-NC. n = 13.
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