Comparison of patients with persistent post-COVID-19 headaches between those who fulfilled and those who did not fulfill the criteria for chronic daily headache (CDH)

Characteristics With CDH (n = 25) Without CDH (n = 39) P value
Age (yr) 51 (44;59.5) 48 (39;56.5) 0.413
Female 20/25 (80) 19/39 (49) 0.012
Previous headache 18/25 (72) 21/39 (54) 0.146
Needed to be hospitalized during acute phase of COVID-19 20/25 (80) 26/39 (66) 0.247
Headache characteristics
Intensity 8 (8;9.5) 8 (5.5;10) 0.061
Bilateral 21/25 (84) 35/39 (90) 0.498
Pulsatile 11/24 (46) 28/39 (72) 0.039
Worsening through exercise 13/25 (52) 22/39 (56) 0.729
Phonophobia 21/25 (84) 25/39 (64) 0.084
Photophobia 19/25 (76) 24/39 (61) 0.229
Nausea 19/25 (76) 24/39 (61) 0.229
Vomiting 10/25 (40) 13/39 (33) 0.587
Headache Impact Test (HIT-6) 67 (55;70) 56 (48;65) 0.018
Headache duration
> 120 days 21/25 (84) 21/39 (54) 0.013
> 360 days 18/25 (72) 19/39 (49) 0.066

Values are presented as number (%) or median (P25;P75).

P25: 25th percentile, P75: 75th percentile.

Korean J Pain 2024;37:247~255 https://doi.org/10.3344/kjp.24046
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