Equianalgesic doses of commonly prescribed opioids

Opioids Ratio to calculate MME (multiply by) 30 MME dose, mg/day 50 MME dose, mg/day
Morphine 1 30 50
Oxycodone 1.5–2 15–20 25–33
Hydromorphone 4 7.5 12.5
Hydrocodone 1–0.67 30–45 50–75
Codeine 0.15 200 333
Tapentadol 0.4 75 125
Fentanyl transdermal patch (in mcg/hr) 2.4 12a NA

MME: morphine milligram equivalent, NA: not applicable.

aBy calculation, the dose of transdermal fentanyl patch corresponding to 30 MME/day should be 12.5 mcg/hr, however, it was rounded down to the closest equivalent dose that is commercially available.

Korean J Pain 2024;37:119~131 https://doi.org/10.3344/kjp.24022
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