Fig. 2. (A, B) Changes in PWTL and PWMT after RIH. PWTL (A) and PWMT (B) were measured in rats at 24 hour before (baseline) and at 4, 8, 24, and 48 hour post-remifentanil infusion (mean ± standard deviation, n = 6 per group, one-way ANOVA). PWTL: paw withdrawal thermal latency, PWMT: paw withdrawal mechanical threshold, RIH: remifentanil-induced hyperalgesia. ***P < 0.001 compared with baseline. ###P < 0.001 compared with group control.
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