Fig. 6. Effects of intra-medial prefrontal cortex microinjection of normal saline (NS), L-arginine (L-Arg), N(gamma)-nitro-L-arginine methyl ester (L-NAME) and opioid antagonists on photo beam breaks number in spared nerve injury (SNI) rats. Values represent the mean ± SEM (n = 6 animals per group). Similar letters indicate no significant differences among groups (one way ANOVA and Tukey’s post hoc tests). LA: L-Arg, Nlz: naloxonazine, Ntd: naltrindole, Nbt: nor-binaltorphimine, SEM: standard error of the mean, ANOVA: analysis of variance.
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