Fig. 6. Western blot analysis showing changes in CXCL13, CXCR5, and GAT-1 levels of the spinal cord at 10, 14, and 21 days after surgery. Treatment with botulinum toxin type A (BTX-A) prevented the increase in CXCL13, CXCR5, and GAT-1 proteins as graphed in A, B, C, and D. The error bar means mean ± standard deviation. CCI: chronic constriction injury, CXCL13: chemokine ligand 13, CXCR5: C-X-C chemokine receptor type 5, GAT-1: GABA transporter 1. aP < 0.05 vs. CCI + normal saline (NS) group, One-way ANOVA, n = 3 in each group.
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