Table. 1.

Free energy of binding among compounds found in Ononis spinosa leaf extract and the co-crystallised ligand (capsazepine)

Compound % Free energy of binding
(kcal/mol)
Campesterol 1.9 –11.73
Stigmasterol 2.7 –11.02
Cycloartenol 5.1 –9.59
Ononin 20.5 –8.91
Medicarpin-3-o-glucoside 1.8 –8.84
Biochanin-A 0.9 –8.46
Biochanin 1.0 –8.44
(-)-Maackiain-3-o-glucoside/Trifolirhizin 6.4 –8.34
Rhoifolin 3.6 –8.28
Formononetin 3.8 –8.03
Tectorigenin 3.3 –7.91
Apigenin 1.5 –7.52
Quercetin 5.1 –7.07
Quercitrin 3.0 –7.07
Ferulic-acid 2.6 –7.03
Genistein 1.8 –6.90
Kaempferol 0.88 –6.69
Myricitrin 6.1 –6.31
Vitexin 0.66 –6.31
Gentisic-acid 5.4 –6.16
Gallic-acid 4.6 –5.90
Rutoside 0.95 –5.59
Hyperoside 0.36 –5.57
Korean J Pain 2021;34:262~270 https://doi.org/10.3344/kjp.2021.34.3.262
© Korean J Pain