Fig. 1. Assessment of the streptozotocin (STZ)-induced diabetes model. (A) Hyperglycemia was developed in rats 3-5 weeks after STZ administration. (B, C) Both paw withdrawal threshold (PWT) and paw withdrawal latency (PWL) were significantly decreased 3 to 5 weeks following STZ injection. The error bars indicate standard deviation. aP < 0.05 and bP < 0.01 vs. control rats.
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