The Korean Journal of Pain 2020; 33(1): 3-12
Published online January 1, 2020 https://doi.org/10.3344/kjp.2020.33.1.3
Copyright © The Korean Pain Society.
1Department of Pharmacoeconomics and Pharmaceutical Administration, Tehran University of Medical Sciences, Tehran, Iran
2Department of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
3Department of Health Administration and Public Health, John G. Rangos School of Health Sciences, Duquesne University, Pittsburgh, PA, USA
4Department of Biostatistics and Epidemiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Correspondence to:Bahman Amani
Department of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Qods St., Keshavarz Blvd., Tehran 00982113, Iran
Received: July 18, 2019; Revised: December 10, 2019; Accepted: December 10, 2019
This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Neuropathic pain after spinal cord injury (SCI) has a significant negative impact on the patients’ quality of life. The objective of this systematic review is to examine the safety and efficacy of pregabalin (PGB) and gabapentin (GBP) in the treatment of neuropathic pain due to SCI. PubMed, the Cochrane Library, Embase, Scopus, and the Web of Science were searched up to December 2018. The reference lists of key and review studies were reviewed for additional citations. The quality of the studies was evaluated using the Cochrane Collaboration’s tools for assessing the risk of bias. A meta-analysis was performed for primary and secondary outcomes. Eight studies were eligible for inclusion. Meta-analysis of PGB
Keywords: Anxiety, Depression, Gabapentin, Meta-Analysis, Neuralgia, Pain, Pregabalin, Spinal Cord Injuries, Systematic Review.