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Fig. 2. Paw withdrawal threshold (PWT) across time. The PWT was observed from the 3rd day until the 14th day following spinal nerve ligation (SNL). On the 3rd day after SNL, mechanical allodynia was confirmed. The rats of the gabexate group showed higher PWT than those of the vehicle-treated group during the observation period (P < 0.001). The sham-operation group, sham operation only without SNL or drug; the vehicle-treated group, the control group treated with intraperitoneal normal saline daily after 3rd day following SNL until the end of the study period; the gabexate group, the experimental group treated with intraperitoneal 20 mg/kg of gabexate mesilate daily after 3rd day following SNL until the end of the study period. *P < 0.05 compared with the vehicle-treated group.
The Korean Journal of Pain 2020;33:30~39 https://doi.org/10.3344/kjp.2020.33.1.30
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